hrp0086p2-p574 | Perinatal Endocrinology P2 | ESPE2016

Use of a Cord Blood F-Dex Monocyte Binding Assay to Study the Glucocorticoid Sensitivity in Premature Neonates

Madubuko Adaora , Giuliano Michael , Al-Khan Abdulla , Alvarez Manuel , Alvarez-Perez Jesus , Balboul Sarah , Aisenberg Javier , Ghanny Steven

Background: Glucocorticoids play an important role in the developing fetus; the most important of which is lung maturation by increasing surfactant production and release. Glucocorticoid receptor (GR) functioning changes throughout the fetal period, especially during the transition to extrauterine life. Given the importance of glucocorticoids in lung development and functioning, studying glucocorticoid sensitivity (GS) in this population would be helpful, especially in the pre...